XCMS is the most cited software for processing untargeted metabolomics data, offering tools for peak picking, retention time alignment, and metabolite identification. Depending on your technical expertise, you can access its features through a local R installation or a cloud-based web interface. Choose Your XCMS Platform
Before downloading the package, you must have the latest version of the R programming language installed. It is highly recommended to use Posit RStudio as your integrated development environment (IDE). 2. Configure BiocManager
A cloud-based platform that requires no local installation. It provides a guided wizard for data upload and visualization.
Researchers typically choose between the local R package for maximum customization or the online version for ease of use.
A commercial desktop version offered by SCIEX for integrated workflows. Step-by-Step Local Installation
XCMS is hosted on the Bioconductor repository, not CRAN. You must first install the BiocManager tool to access it. XCMSPlus Software - SCIEX
Ideal for power users who need to build custom pipelines, handle large batches, or integrate with other Bioconductor tools.