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: They can occur in coding regions (exons), non-coding regions (introns), or between genes. Why SNPs Matter in Medicine
At its core, a SNP represents a single-letter swap in the genetic code. For example, in a specific stretch of DNA, most individuals might have the base , but a smaller portion of the population might have thymine (T) at that exact position. To be classified as a SNP, this variation must occur in at least 1% of the population. : They can occur in coding regions (exons),
A single-nucleotide polymorphism (SNP) is a genetic variation occurring when a single nucleotide—the basic building block of DNA—differs between members of a species or paired chromosomes in an individual. Pronounced like the word "snip," these tiny variations are the most common form of genetic difference among people, occurring roughly once in every 1,000 nucleotides. What Exactly is a SNP? To be classified as a SNP, this variation
: Most SNPs involve only two possible nucleotides (e.g., C or T). What Exactly is a SNP